The Splendid Magic of Penny Arcade by Mike Krahulik and Jerry Holkins
Penny Arcade is one of my go-to webcomics, despite my being a gamer who only perks up when a new Zelda title is released and can’t bring herself to play Left 4 Dead 2, despite the fact that Ellis is pretty much the funniest character ever. It’s often vulgar and always hilarious, but it doesn’t solely depend on gaming humor. Some of the funniest things the webcomic has ever done are more surreal than anything else.
The Literary Omnivore 